Health experts have been trying to establish a link between vitamin D and cancer for ages. Many health studies have shown that people who reside close to the equator where exposure to sunlight generates more vitamin D are at a lower risk of certain cancers and death. Experts have seen that vitamin D delays the progression of cancer in the infected cells of mouse models in the lab. However, the findings of randomized clinical trials on humans have not shown any clear signs. The Vitamin D and Omega-3 Trial (VITAL), which has been done in 2018 has shown that vitamin D might not be able to reduce the risk of cancer but it surely reduces the risk of death due to certain cancers. Now, in the second analysis of VITAL, experts have examined the link between having vitamin D supplements and metastatic cancer. The second analysis has been done by experts from Brigham and Women Hospital. The findings of the study have been released in the journal JAMA Network.
Experts have clearly stated in the study that vitamin D is linked with a 17 percent reduction for advanced-stage cancer. Scientists have found a nearly 38 percent reduced risk of advanced cancer among people who have normal body mass index (BMI). It suggests that BMI affects the link between vitamin D and reduced risk of advanced-stage cancer. The co-author of the study, Dr. Paulette Chandler has said that the findings show that vitamin D might reduce the risk of rising advanced-stage cancer. He has said that vitamin D supplements are inexpensive and easily available around the world. The VITAL study has been a thorough placebo-controlled study, which has taken place over a span of five years. The study has enrolled men who are 50 years and above and women who are 55 years old and above. No participant has been diagnosed with cancer at the beginning of the study. All the participants have been racially and ethnically different. The research has been designed to assess the effects of vitamin D and Omega-3 and the interaction between the two elements.
In the secondary analysis of the study, experts have looked at the potential reduction in the rate of cancer deaths in people who have been taking vitamin D supplements. They have compared the findings of the study by examining the risk of advanced-stage cancer in people who have not been taking vitamin D supplements. They as well have observed the effect of varied BMI among people. Experts have found that out of more than 25000 participants in the VITAL study, around 1617 people have been diagnosed with fatal cancer in the next five years. Around 226 out of 13000 people who have been given vitamin D supplements have been diagnosed with advanced-stage cancer. At the same time, nearly 274 people have been diagnosed with fatal cancer, who have been taking placebo. Out of 7843 people with normal BMI, who have received vitamin D add-on, only 58 people have been identified with advanced cancer. Past studies as well have shown that cancer patients have a 72 percent higher level of vitamin D deficiency.